INCREASED NUCLEIC ACID-GUIDED CELL EDITING VIA LEXA-RAD51 FUSION PROTEIN

• Main Authors: GANDER MILES, SPINDLER EILEEN, TIAN TIAN
• Format: Patent
• Language: Chinese; English
• Published: 25.02.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present disclosure provides compositions and methods to increase the percentage of edited yeast cells in a cell population when employing nucleic acid-guided editing, and automated multi-module instruments for performing these methods. Thus, there is provided in one embodiment an editing vector...