USE OF NEUTROPHIL ELASTASE INHIBITORS IN LIVER DISEASE

The invention relates to methods for treating chronic liver disease, in particular nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), with neutrophil elastase inhibitors. The invention further relates to pharmaceutical compositions comprising neutrophil elastase inhibi...

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Bibliographic Details
Main Authors SATYAL SANJEEV, SAVAGE SCOTT, B. ROBERTS, HUH HOYOUNG, WANG XUEYAN
Format Patent
LanguageChinese
English
Published 05.11.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to methods for treating chronic liver disease, in particular nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), with neutrophil elastase inhibitors. The invention further relates to pharmaceutical compositions comprising neutrophil elastase inhibitors. 本发明涉及使用中性粒细胞弹性蛋白酶抑制剂治疗慢性肝病、特别是非酒精性脂肪肝病(NAFLD)和非酒精性脂肪性肝炎(NASH)的方法。本发明还涉及包含中性粒细胞弹性蛋白酶抑制剂的药物组合物。
Bibliography:Application Number: CN201980040583