DETERMINING FREQUENCY FOR TTFIELDS TREATMENT BASED ON ELECTRICAL CHARACTERISTIC OF TARGETED CANCER CELLS

• Main Authors: GILADI MOSHE, ZEEVI EINAV, BOMZON ZEEV, WENGER CORNELIA
• Format: Patent
• Language: Chinese; English
• Published: 29.10.2021
• Subjects: ELECTROTHERAPY; HUMAN NECESSITIES; HYGIENE; MAGNETOTHERAPY; MEDICAL OR VETERINARY SCIENCE; RADIATION THERAPY; ULTRASOUND THERAPY

Cancer treatment using TTFields (Tumor Treating Fields) can be customized to each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic (e.g., dielectrophoretic forces, cell membrane capacitance, etc.) of the cancer cells, determining a frequency for the TTFields based on the determined electrical characteristic, and treating the cancer by applying TTFields to the subject at the determined frequency. In addition, cancer treatment can be planned for each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic of the cancer cells, predicting whether TTFields would be effective to treat the cancer based on the determined electrical characteristic, and treating the subject by applying TTFields if the prediction indicates that TTFields would be effective. 使用TTField(肿瘤治疗场)的癌症治疗可以针对每个个体受试者定制，通过从受试者获得癌细胞，确定癌细胞的电特性(例如，介电电泳力、细胞膜电容等)，基于所确定的电特性确定用于TTField的频率，以及通过以所确定的频率将TTField施加于受试者来治疗癌症。此外，可以为每个个体受试者计划癌症治疗，通过从受试者获得癌细胞，确定癌细