一种检测肿瘤产生原始生殖细胞能力和效率的方法及用途

• Format: Patent
• Language: Chinese
• Published: 22.08.2025
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

本发明属生物和医学检验技术领域，涉及检测肿瘤产生PGC样细胞能力和效率的方法，具体涉及一种检测肿瘤产生原始生殖细胞(Primordial germ cells,PGCs)样肿瘤细胞的能力的方法，本发明采用肿瘤组织或肿瘤组织培养物，检测其中原始生殖细胞(Primordial germ cells,PGCs)样肿瘤细胞的存在和/或形成效率，以及应用检测肿瘤组织及肿瘤组织培养物中与激活PGC样肿瘤细胞形成相关基因表达的变化，进一步用于预测肿瘤的转移能力和转移风险。 The invention belongs to the technical field of biological and medical examination, and relates to a method for detecting the capability and efficiency of tumors to generate PGC-like cells, in particular to a method for detecting the capability of the tumors to generate the PGCs-like tumor cells. According to the method, tumor tissues or tumor tissue cultures are adopted, the existence and/or formation efficiency of the PGC-like tumor cells are detected, and changes of gene expression related to activation of formation of the PGC-like tumor cells in the tumor tissues and tumor tissue cultures are detected, and the method is further used for predicting the metastasis capability and metastasis risk of the tumors.