Preparation method of raspberry ketone

• Main Authors: LIU BENGEN, NING YUFENG, REN SHUN, LI CONGCONG, XU TIANLONG, FANG WANJUN, MA XIAO, MA SHIMIN
• Format: Patent
• Language: Chinese; English
• Published: 06.08.2021
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention relates to a preparation method of raspberry ketone. The preparation method comprises the step of reacting phenol with butanone alcohol under the action of an organic acid catalyst and a crown ether cocatalyst to obtain the target product raspberry ketone. The raspberry ketone prepared by the method is high in yield, the molar yield can reach up to 91.96% (according to the consumption molar number of butanone alcohol), meanwhile, the dosage of the organic acid catalyst in the preparation method is small, the generation of three wastes can be effectively reduced, and the method has great economic benefits and environmental protection benefits. 本发明涉及一种覆盆子酮的制备方法，包括：在有机酸催化剂和冠醚助催化剂作用下，苯酚和丁酮醇反应，得到目标产物覆盆子酮。该方法制备的覆盆子酮收率高，摩尔收率可高达91.96％(以丁酮醇消耗摩尔数计)，同时该制备方法中有机酸催化剂的用量少，可以有效降低三废的产生，具有较大的经济效益和环保效益。