Special primers for detecting SNP sites of drug-resistance related genes for anticoagulant and antiplatelet medication

• Main Authors: ZHAO MEI, HUANG LIN, FENG YUFEI, ZHENG FANGFANG, SONG JUNXIAN
• Format: Patent
• Language: Chinese; English
• Published: 26.03.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention belongs to the technical field of biology, and provides a special primer for detecting SNP sites of drug-resistance related genes for anticoagulant and antiplatelet medication. The special primer comprises a primer group 1 and a primer group 2, wherein the primer group 1 is a specific PCR primer composed of 15 pairs of primers, and the primer group 2 is a single base extension primercomposed of 15 primers. The invention further provides a reparation for detecting the SNP sites of drug-resistance related genes for anticoagulant and antiplatelet medication, and a method for detecting the SNP sites of the drug-resistance related genes for anticoagulant and antiplatelet medication. By adopting the special primer provided by the invention, the detection time can be greatly shortened, the cost is saved, and the special primer has a very high application value for guiding precise medication of six clinically common anticoagulant and antiplatelet drugs, and is suitable for popularization and application