Pharmaceutical composition with improved bioavailability

The invention relates to solid dispersions of poorly water soluble compounds, in particular 4-{[(2R, 3S, 4R, 5S)-4-(4-chloro-2-fluorophenyl)-3-(3-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-pyrrolidine-2-carbonyl]amino}-3-methoxy-benzoic Acid, formed by solvent co-precipitation or spray dr...

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Bibliographic Details
Main Authors SHAH NAVNIT HARGOVINDAS, MA HUA, ZHANG YU-E, LOMUSCIO STEVE, MATCHETT MICHAEL ALLEN, SANDHU HARPREET K
Format Patent
LanguageChinese
English
Published 19.02.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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