具有高度非辐射衰减抑制的碗烯包裹的AIE纳米点用于增强体内癌症光诊疗

本发明主题涉及具有聚集诱导发光(AIE)性质并表现出近红外吸收的荧光化合物。包括本发明化合物的组合物可包括碗烯改性的聚乙二醇封装基质。该组合物可以是纳米粒子形式。将AIE化合物封装在碗烯基质中提供了粒子内刚性并限制了被封装AIE化合物的分子内转动，这导致该组合物在体内荧光和ROS生成能力增强。因此，该组合物可用于NIR成像引导的癌症手术和光动力癌症治疗。 The present subject matter relates to fluorescent compounds that have aggregation-induced emission (AIE) characteristics...

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Bibliographic Details
Format Patent
LanguageChinese
Published 18.07.2023
Subjects
ADHESIVES
CHEMISTRY
DYES
MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE
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