Blood vessel model

• Main Authors: NEVILLE CRAIG, SUNDBACK CATHRYN, ITO KOJU, SUEHIRO TAKAFUMI, MIMA SHINJI, KAKINUMA CHIHAYA, HIKIMOTO DAICHI
• Format: Patent
• Language: Chinese; English
• Published: 09.06.2020
• Subjects: ADDITIVE MANUFACTURING TECHNOLOGY; ADDITIVE MANUFACTURING, i.e. MANUFACTURING OFTHREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVEAGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING,STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING; ADVERTISING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE; CHEMISTRY; COMPOSITIONS BASED THEREON; CRYPTOGRAPHY; DIAGRAMS; DISPLAY; EDUCATION; EDUCATIONAL OR DEMONSTRATION APPLIANCES; GENERAL PROCESSES OF COMPOUNDING; GLOBES; LAYERED PRODUCTS; LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; PERFORMING OPERATIONS; PHYSICS; PLANETARIA; SEALS; THEIR PREPARATION OR CHEMICAL WORKING-UP; TRANSPORTING; WORKING-UP

The present disclosure provides a blood vessel model including: a pair of channel members, mutually opposing each other, each of which includes an opposing face in which a respective microchannel is formed; and a porous membrane that includes plural through-holes penetrating in a thickness direction, that is disposed between the opposing faces of the pair of channel members, and that partitions between the microchannels, wherein the porous membrane is provided with a vascular endothelial cell layer so as to cover one face facing one of the microchannels, an average opening diameter of the through-holes is from 1 [mu]m to 20 [mu]m, and an opening coverage ratio of the through-holes is from 30% to 70%. 本发明提供一种血管模型，其包括：一对通道部件，彼此相对且各通道部件包含形成有各自的通道的相对面；及多孔膜，包括沿厚度方向贯穿的多个贯穿孔，并且配置于一对通道部件的相对面之间，且将微通道之间隔开，其中，所述多孔膜设置有血管内皮细胞层以覆盖与微通道中的一个相对的表面，所述贯穿孔的平均开口直径为1μm～20μm，贯穿孔的开口覆盖率为30％～70％。