Polymeric sorbent, preparation and use thereof

The invention relates to polymer chemistry, specifically to polymer sorbents intended for selective removing cytokines and bacterial endotoxins from whole blood and other body liquids, in particular blood plasma, lymph etc., as well as from aqueous protein solutions and aqueous organic compound solu...

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Main Authors MOROZOV ALEXEY SERGEEVICH, BESSONOV IVAN VIKTOROVICH, KOPITSYNA MARIA NIKOLAEVNA
Format Patent
LanguageChinese
English
Published 07.01.2020
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Abstract The invention relates to polymer chemistry, specifically to polymer sorbents intended for selective removing cytokines and bacterial endotoxins from whole blood and other body liquids, in particular blood plasma, lymph etc., as well as from aqueous protein solutions and aqueous organic compound solutions, also containing inorganic salts, as well as to method of producing such sorption materials and the method of sorbtion processing liquids using the polymer sorbents. Technical result consists in providing a sorbent that is able to remove both cytokines and bacterial endotoxins, in improving selectivity of the polymer sorbents in respect to the compounds as well as in providing a simple and effective method of producing the sorbent. 本发明涉及聚合物化学,特别涉及旨在从全血和其他体液(尤其是血浆、淋巴等),以及从还包含无机盐的有机化合物水溶液和蛋白质水溶液中选择性地除去细胞因子和细菌内毒素的聚合物吸着剂,以及涉及产生这样的吸着材料的方法和使用所述聚合物吸着剂对液体进行吸着处理的方法。技术结果在于提供能够除去细胞因子和细菌内毒素二者的吸着剂,在于提高所述聚合物吸着剂对于所述化合物的选择性,以及在于提供产生所述吸着剂的简单且有效的方法。
AbstractList The invention relates to polymer chemistry, specifically to polymer sorbents intended for selective removing cytokines and bacterial endotoxins from whole blood and other body liquids, in particular blood plasma, lymph etc., as well as from aqueous protein solutions and aqueous organic compound solutions, also containing inorganic salts, as well as to method of producing such sorption materials and the method of sorbtion processing liquids using the polymer sorbents. Technical result consists in providing a sorbent that is able to remove both cytokines and bacterial endotoxins, in improving selectivity of the polymer sorbents in respect to the compounds as well as in providing a simple and effective method of producing the sorbent. 本发明涉及聚合物化学,特别涉及旨在从全血和其他体液(尤其是血浆、淋巴等),以及从还包含无机盐的有机化合物水溶液和蛋白质水溶液中选择性地除去细胞因子和细菌内毒素的聚合物吸着剂,以及涉及产生这样的吸着材料的方法和使用所述聚合物吸着剂对液体进行吸着处理的方法。技术结果在于提供能够除去细胞因子和细菌内毒素二者的吸着剂,在于提高所述聚合物吸着剂对于所述化合物的选择性,以及在于提供产生所述吸着剂的简单且有效的方法。
Author BESSONOV IVAN VIKTOROVICH
MOROZOV ALEXEY SERGEEVICH
KOPITSYNA MARIA NIKOLAEVNA
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Snippet The invention relates to polymer chemistry, specifically to polymer sorbents intended for selective removing cytokines and bacterial endotoxins from whole...
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SubjectTerms CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
Title Polymeric sorbent, preparation and use thereof
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