Lotus seed starch-chitosan composite hemostatic powder and preparation method thereof

• Main Authors: ZENG HONGLIANG, LIN YAN, ZHENG MINGJING, LUO MENGLIN, ZHANG YI, ZENG SHAOXIAO, ZHENG BAODONG, YOU QINGXIANG
• Format: Patent
• Language: Chinese; English
• Published: 29.03.2019
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

The present invention relates to the field of medical hemostatic materials and aims to provide lotus seed starch-chitosan composite hemostatic powder and a preparation method thereof. The preparationmethod comprises the following steps: step 1: after chitosan and ultrapure water are mixed, stirring and hydrating are conducted for 5-7 h to obtain a chitosan solution; step 2: lotus seed starch is added in the chitosan solution of the step 1 to be mixed, and after heating and stirring at 70-90 DEG C for 5-10 min, autoclaved sterilization is conducted obtain composite liquid; and step 3: a pore-foaming agent is added the obtained composite liquid of the step 2, then a microfluidic treatment is conducted, and then ultraviolet sterilization is conducted to obtain the lotus seed starch-chitosancomposite hemostatic powder. The prepared lotus seed starch-chitosan composite hemostatic powder has a porous structure, and is rapid in hemostasis and also high in biological activity. 本发明涉及医用止血材料领域，目的在于提供种莲子淀粉-壳聚糖复合止血粉及其制备方法