ANTI-PD-L1 ANTIBODIES

• Main Authors: CAMPBELL JAMIE, SANDY NIKOLE, ARKINSTALL STEPHEN JOHN, GERMASCHEWSKI VOLKER, DEANTONIO CECILIA, KIRBY IAN, GALLAGHER THOMAS, VAN KRINKS CASSANDRA, KOSMAC MIHA, GILLIES STEPHEN DOUGLAS
• Format: Patent
• Language: Chinese; English
• Published: 15.03.2019
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to anti-PD-L1 antibodies, bispecific antibodies containing one domain with specificity to PD-L1, and to immunocytokines comprising an anti-PD-L1 antibody fused to a cytokine, such as IL-2. The present invention also provides methods of treatment, uses and pharmaceutical...