Novel cancer stem cell killing agent for gastric cancer and application thereof

• Main Authors: LI JINGDUAN, CHEN TIE, CHEN JIAJIE, CHANG GANG, SHU XINGSHENG, LI CHENYANG, WANG SHAOXIANG
• Format: Patent
• Language: Chinese; English
• Published: 18.01.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a novel application of a lipid-lowering drug Evacetrapib in the treatment of gastric cancer tumor stem cells. Using gastric cancer stem cells as a model, we found that Evacetrapib could not only inhibit the growth of gastric cancer cell line, but also promote its apoptosis. I...