SHIP1 modulators and methods related thereto

• Main Authors: RAYMOND JEFFERY R, BOGUCKI DAVID, MACRURY THOMAS B, HARWIG CURTIS, KHLEBNIKOV VLADIMIR, SHAN RUDONG, MACKENZIE LYOYD F, PETTIGREW JEREMY D
• Format: Patent
• Language: Chinese; English
• Published: 06.11.2018
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Compounds of formula (I): [Formula should be inserted here]; where [Formula should be inserted here], n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used...