Method for preparing betrixaban intermediate

• Main Authors: SUN DEXIN, ZHANG GUIMIN, BAI WENQIN
• Format: Patent
• Language: Chinese; English
• Published: 09.03.2018
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention provides a method for preparing a betrixaban intermediate. The method comprises the following step of using 5-methoxyl-2-nitrobenzoic acid and 2-amino-5-chloropyridine as initiating rawmaterials, so as to prepare N-(5-chloro-2-pyridyl)-5-methoxyl-2-nitrobenzoic acid. The method has the...