Paragonimus skrjabini infection immunologic diagnosis biomarker IL-5 preparation method

• Main Authors: XU LINA, WU MALI, GUO ZHILAI, LI ANMEI, HUANG YUTING, LUO WEI
• Format: Patent
• Language: Chinese; English
• Published: 15.09.2017
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The present invention discloses a new molecule IL-5 for immunologic diagnosis of foodborne trematoda, and a preparation method of the new molecule IL-5 in final diagnosis and treatment effect evaluation of Paragonimus skrjabini infections of juvenile under 15 years old. According to the present invention, the diagnosis result is positive when the IL-5 concentration is increased by more than two times compared to the health human, and after the patient takes praziquantel three days according to the dose of 1/kg body weight, the IL-5 concentration returns to the normal value; and the IL-5 is stable, specific, sensitive, rapid, simple and inexpensive, and can provide good clinical application value for the diagnosis and treatment of Paragonimus skrjabini infection induced paragonimiasis, and the disease diagnosis result obtained according to the multiple of the IL-5 concentration increasing amplitude can be consistent with the clinical symptoms and the epidemiological history survey information so as to easily d