Methods of producing mogrosides and compositions comprising same and uses thereof

• Main Authors: SHEN SHMUEL, KATZIR NURIT, DAVIDOVICH-RIKANATI RACHEL, TADMOR YAAKOV, COHEN SHAHAR, LEWINSOHN EFRAIM, OREN ELAD, BURGER YOSEF, PETREIKOV MARINA, DORON-FAIGENBOIM ADI, ITKIN MAXIM, PORTNOY VITALY, SCHAFFER ARTHUR A
• Format: Patent
• Language: Chinese; English
• Published: 29.08.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), expoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl...