Method for producing arbekacin through one-pot process continuous flow

• Main Authors: CHANG BAOLEI, YANG QINGKUN, LI DECAI, WU KE, CHEN ZHONGNAN, ZHOU XIANGUO
• Format: Patent
• Language: Chinese; English
• Published: 04.07.2017
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; SUGARS

The invention provides a method for producing arbekacin through one-pot process continuous flow. The method is characterized in that a silanization product of dibekacin and active thioester undergo a reaction in a microreactor as initial raw materials. The combination of the active thioester and the...