Anti-factor D antibody variants and uses thereof

• Main Authors: VAN LOOKEREN-CAMPAGNE MENNO, TESAR DEVIN, SCHEER JUSTIN M, KELLEY ROBERT F, HASS PHILIP E
• Format: Patent
• Language: Chinese; English
• Published: 22.03.2017
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. 本发明涉及抗-因子D抗体变体，其制备及其在制备用于治疗与过度或不受控的补体激活相关的疾病和病症的组合物和药物中...