Paper chip used for chemiluminescence time resolution and manufacturing method thereof

• Main Authors: CHU WEIRU, LIU WEI, CHEN YING, ZHAO MEI
• Format: Patent
• Language: Chinese; English
• Published: 21.09.2016
• Subjects: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PHYSICS; TESTING; TRANSPORTING

The invention discloses a paper chip used for chemiluminescence time resolution and a manufacturing method thereof. Each circulation channel except one of the paper chip is covered with polydimethylsiloxane having different lengthes, and the manufacturing method is simple, green and environmentally friendly, and has low cost. The cutting of the paper chip and accurate carving of polydimethylsiloxane can be realized with the only needing of a simple carving machine. The accurate control of the migration rate of the sample in the paper chip is realized by means of controlling the cover capacity of the polydimethylsiloxane by the paper chip, so that the time resolution of the migration rate of the sample can be realized on the premise of the same length of the channel, the chemiluminescence detection of simultaneous determination of different substances is realized, and the used polydimethylsiloxane does not affect the chemiluminescence signal of the reaction. Moreover, the reproducibility of the migration time