A testing method and a testing device for dissolution properties of an active component of a solid preparation

• Main Author: ZENG FANCHU
• Format: Patent
• Language: Chinese; English
• Published: 08.06.2016
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

A testing method and a testing device for dissolution properties of an active component of a solid preparation are provided. By adopting accumulated dissolution of the active component from the solid preparation as at least one independent variable, at least one selected from a dissolution speed of the active components under given hydromechanical and solvent physicochemical property conditions, the average value of the dissolution speed in a given value range of the at least one independent variable, impedance of particles of the preparation to a solvent fluid, and the average value of the impedance in a given value range of the at least one independent variable is measured. 固体制剂活性物溶出性质的测试方法和测试装置，以该活性物从该制剂的累积溶出度为至少自变量，测量下述中的至少员：该活性物在给定流体力学和溶媒理化性质条件下的溶出速度；该溶出速度在所述至少自变量之给定数值范围上的平均值；该制剂的颗粒对溶媒流体的阻抗；和该阻抗在所述至少自变量之给定数值范围上的平均值。