2-substituted imidazo[4,5-D]phenanthroline derivatives and their use in the treatment of cancer

• Main Authors: YOUNG AIPING H, LEE YOON, CUKIER HOWARD, NEDUNURI VENKATA, HUESCA MARIO, PERALTA ROBERT
• Format: Patent
• Language: English
• Published: 03.02.2016
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides 2-substituted imidazo[4,5-d]phenanthroline compounds, which are capable of inhibiting proliferation of one or more renal cancer cells, pancreatic cancer cells, prostate cancer cells, colon cancer cells, leukemia cells, brain cancer/tumour cells or non-small cell lung c...