Method for preparing anti-human R47H-TREM2 mutant human monoclonal antibody

• Main Author: ZHOU XIMING
• Format: Patent
• Language: English
• Published: 06.01.2016
• Subjects: CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

The invention provides a method for preparing an anti-human R47H-TREM2 mutant human monoclonal antibody. The method comprises the following steps that (1) a polypeptide antigen is synthesized, wherein 201 6-15aa R47H-TREM2 polypeptides are artificially synthesized; antigenic determinants are expande...