Drug delivery carrier targeting prostate cancer, drug delivery system and preparation method and application thereof

The invention relates to the technical field of medicine and aims to provide a drug delivery carrier targeting prostate cancer, a drug delivery system and a preparation method and application thereof. The drug delivery carrier can realize double-targeted and simultaneous delivery of drug to prostate...

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Main Authors GAO JING, YAO CHONG, TAI ZONGGUANG, DING BAOYUE, WANG XIANG, LIU JIYONG, WANG XIAOYU, ZHANG LIJUAN, ZHU QUANGANG, GU SHENGYING, WU XIN, DING XUEYING, FAN WEI, GAO SHEN
Format Patent
LanguageEnglish
Published 25.11.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to the technical field of medicine and aims to provide a drug delivery carrier targeting prostate cancer, a drug delivery system and a preparation method and application thereof. The drug delivery carrier can realize double-targeted and simultaneous delivery of drug to prostate cancer cells ADPC and AIPC. The drug delivery carrier comprises a polycation high molecular material, polypeptide targeting hormone-dependent prostate cancer cells, and polypeptide targeting hormone-independent prostate cancer cells. The drug delivery carrier can mediate gene drug to reach prostate cancer tissue, so that expression of the gene drug in the prostate cancer cells is improved effectively.
Bibliography:Application Number: CN20151223717