Preparation method for novel NS5A inhibitor medicine

• Main Authors: HUANG HU, HU HAIYANG, QI XIAOQING, LI ZEBIAO, GU WENCHAO, LIN YANFENG
• Format: Patent
• Language: English
• Published: 23.09.2015
• Subjects: CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

The invention discloses a preparation method for novel NS5A inhibitor medicine. The preparation method includes the steps that step1, (1R, 3S, 4S)-3-(6-bromine-1H-benzimidazole-2-base)-2- azabicyalo (2.2.1) heptane-2-carboxylic acid tert-butyl ester serves as raw materials and reacts with bis (pinac...