Chrysin and amine cyclodextrin clathrate

The invention discloses a flavonoid chrysin and amine cyclodextrin clathrate, the amine cyclodextrin is amino-substituted beta-cyclodextrin, amine cyclodextrin and chrysin can generate clathration, ionic interaction of amine cyclodextrin and a phenolic hydroxyl group in amino and chrysin molecular s...

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Bibliographic Details
Main Authors NIU RAOMEI, GAO KAI, YANG BO, YANG TONGZE, YANG JIAN, LIAO XIALI
Format Patent
LanguageEnglish
Published 12.08.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention discloses a flavonoid chrysin and amine cyclodextrin clathrate, the amine cyclodextrin is amino-substituted beta-cyclodextrin, amine cyclodextrin and chrysin can generate clathration, ionic interaction of amine cyclodextrin and a phenolic hydroxyl group in amino and chrysin molecular structure is generated, chrysin water solubility of chrysin can be greatly increased, and a chrysin liquid preparation is conveniently formed. The clathrate has the advantages of water solubility, good stability and good external antineoplastic activity. The preparation method is simple, condition is mild, operation is easy, the method can be used for developing a novel chrysin preparation, and has important practical value.
Bibliography:Application Number: CN201510167884