Use of a topical composition containing epidermal growth factor (EGF) for diabetic foot amputation prevention
The present invention is related to the use of topical formulations that contain epidermal growth factor (EGF) encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English |
| Published |
20.05.2015
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention is related to the use of topical formulations that contain epidermal growth factor (EGF) encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in contrast with the previous art, are useful because they provide a high bioavailability of EGF in the tissue deep below the lesions and for preventing diabetic foot amputation. |
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| AbstractList | The present invention is related to the use of topical formulations that contain epidermal growth factor (EGF) encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in contrast with the previous art, are useful because they provide a high bioavailability of EGF in the tissue deep below the lesions and for preventing diabetic foot amputation. |
| Author | BETANCOURT RODRIQUEZ BLAS YAMIR PAEZ MEIRELES ROLANDO PUPO ESCALONA ELDER BERLANGA ACOSTA JORGE AMADOR |
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| Snippet | The present invention is related to the use of topical formulations that contain epidermal growth factor (EGF) encapsulated in or associated to deformable or... |
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| SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | Use of a topical composition containing epidermal growth factor (EGF) for diabetic foot amputation prevention |
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