Use of a topical composition containing epidermal growth factor (EGF) for diabetic foot amputation prevention

The present invention is related to the use of topical formulations that contain epidermal growth factor (EGF) encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in...

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Bibliographic Details
Main Authors PUPO ESCALONA ELDER, BETANCOURT RODRIQUEZ BLAS YAMIR, BERLANGA ACOSTA JORGE AMADOR, PAEZ MEIRELES ROLANDO
Format Patent
LanguageEnglish
Published 20.05.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is related to the use of topical formulations that contain epidermal growth factor (EGF) encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in contrast with the previous art, are useful because they provide a high bioavailability of EGF in the tissue deep below the lesions and for preventing diabetic foot amputation.
Bibliography:Application Number: CN201510005113