Nose powder inhalation for treating epilepsy and preparation method thereof

• Main Authors: ZHU HUAXU, GUO LIWEI, LU JIN, FU TINGMING, QIAN YUYI
• Format: Patent
• Language: Chinese; English
• Published: 26.03.2014
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses nose powder inhalation for treating epilepsy and a preparation method thereof. The nose powder inhalation consists of alpha-asarone powder conforming to the nasal delivery; the particle size of the powder is greater than 5 microns, but not greater than 200 microns, preferably in the range of 10-100 microns; the preparation method comprises the following steps: alpha-asarone raw materials are smashed by air streams to form the alpha-asarone powder conforming to the nasal delivery. The preparation method prepares the alpha-asarone into the powder which conforms to the requirements of the nose powder inhalation; compared with the oral preparations, the nose powder inhalation obviously improves the bioavailability while treating the epilepsy; compared with the injections, the nose powder inhalation reduces the caused allergic reactions and the patient pain caused by the injection administration as containing no accessory, decreases the distribution in the live tissue, reduces the toxic and