Linker and support for solid phase synthesis of nucleic acid

Provided are a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3' terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. A linker for solid phase synthesis of nucleic acid, containing a compound...

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Main Authors MINOMI KENJIRO, MORI KENJIRO, SUZUKI NORITAKA, TSUKAMOTO MASAKI, MAETA ERI, HAYAKAWA YOSHIHIRO
Format Patent
LanguageChinese
English
Published 31.07.2013
Subjects
CHEMISTRY
COMBINATORIAL CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
SUGARS
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Abstract Provided are a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3' terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. A linker for solid phase synthesis of nucleic acid, containing a compound represented by the following formula wherein each symbol is as defined in the specification, is provided.
AbstractList Provided are a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3' terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. A linker for solid phase synthesis of nucleic acid, containing a compound represented by the following formula wherein each symbol is as defined in the specification, is provided.
Author MAETA ERI
SUZUKI NORITAKA
MORI KENJIRO
TSUKAMOTO MASAKI
MINOMI KENJIRO
HAYAKAWA YOSHIHIRO
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NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
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Snippet Provided are a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3' terminal, a universal support carrying the linker, and a...
SourceID epo
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SubjectTerms CHEMISTRY
COMBINATORIAL CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
SUGARS
THEIR PREPARATION OR CHEMICAL WORKING-UP
Title Linker and support for solid phase synthesis of nucleic acid
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