Combination of drugs with protein-binding prodrugs
The present invention relates to a composition and a combination comprising at least one first drug and at least one protein-binding prodrug, wherein the proteinbinding prodrug comprises a protein-binding group, a second drug, and a linker that can be cleaved hydrolytically, enzymatically, or in a p...
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Format | Patent |
Language | Chinese English |
Published |
20.02.2013
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Subjects | |
Online Access | Get full text |
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Abstract | The present invention relates to a composition and a combination comprising at least one first drug and at least one protein-binding prodrug, wherein the proteinbinding prodrug comprises a protein-binding group, a second drug, and a linker that can be cleaved hydrolytically, enzymatically, or in a pH-dependent manner in the body, as well as to a kit and a pharmaceutical composition comprising said composition or combination. |
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AbstractList | The present invention relates to a composition and a combination comprising at least one first drug and at least one protein-binding prodrug, wherein the proteinbinding prodrug comprises a protein-binding group, a second drug, and a linker that can be cleaved hydrolytically, enzymatically, or in a pH-dependent manner in the body, as well as to a kit and a pharmaceutical composition comprising said composition or combination. |
Author | KRATZ FELIX |
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RelatedCompanies | KTB TUMORFORSCHUNGS GMBH |
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Snippet | The present invention relates to a composition and a combination comprising at least one first drug and at least one protein-binding prodrug, wherein the... |
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Title | Combination of drugs with protein-binding prodrugs |
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