Radiolabeled compounds and methods thereof

The present invention relates to radiodiagnostic compounds, methods of making those compounds, and methods of use thereof as imaging agents for preferably a HA serotonin 5-HT1A receptor for use in PET or SPECT, preferably PET. Compositions comprising an imaging-effective amount of radiolabeled compo...

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Main Authors NEWINGTON IAN MARTIN, JINTO JOSE, VARADARAJAN SUNDERARAMAN, BETTS HELEN, MANDAL SUBRATA, WYNN DUNCAN GEORGE, RANGASWAMY CHITRALEKHA, NAIRNE ROBERT JAMES DOMETT, DAVIS REBECCA, GUILBERT BENEDICTE
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LanguageChinese
English
Published 06.02.2013
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Abstract The present invention relates to radiodiagnostic compounds, methods of making those compounds, and methods of use thereof as imaging agents for preferably a HA serotonin 5-HT1A receptor for use in PET or SPECT, preferably PET. Compositions comprising an imaging-effective amount of radiolabeled compounds are also disclosed. The present invention also relates to non-radiolabeled compounds, methods of making those compounds, and methods of use thereof to treat various neurological and/or psychiatric disorders.
AbstractList The present invention relates to radiodiagnostic compounds, methods of making those compounds, and methods of use thereof as imaging agents for preferably a HA serotonin 5-HT1A receptor for use in PET or SPECT, preferably PET. Compositions comprising an imaging-effective amount of radiolabeled compounds are also disclosed. The present invention also relates to non-radiolabeled compounds, methods of making those compounds, and methods of use thereof to treat various neurological and/or psychiatric disorders.
Author RANGASWAMY CHITRALEKHA
VARADARAJAN SUNDERARAMAN
JINTO JOSE
BETTS HELEN
WYNN DUNCAN GEORGE
NAIRNE ROBERT JAMES DOMETT
GUILBERT BENEDICTE
DAVIS REBECCA
MANDAL SUBRATA
NEWINGTON IAN MARTIN
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– fullname: BETTS HELEN
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– fullname: WYNN DUNCAN GEORGE
– fullname: RANGASWAMY CHITRALEKHA
– fullname: NAIRNE ROBERT JAMES DOMETT
– fullname: DAVIS REBECCA
– fullname: GUILBERT BENEDICTE
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Snippet The present invention relates to radiodiagnostic compounds, methods of making those compounds, and methods of use thereof as imaging agents for preferably a HA...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Radiolabeled compounds and methods thereof
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