Chemical process

The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and...

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Main Authors MONTGOMERY FRANCIS JOSEPH, GOLDEN MICHAEL DAVID, WRIGHT NICHOLAS CARTWRIGHT ALE, MARTIN DAVID MICHAEL GLANVILLE, SQUIRE CHRISTOPHER JOHN, BLIXT JOERGEN, PATEL ZAKARIYA, SEPENDA GEORGE JOSEPH, PITTAM JOHN DAVID, HOGAN PHILIP JOHN
Format Patent
LanguageChinese
English
Published 20.06.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4- bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
Bibliography:Application Number: CN201110159729