Diacylethylenediamine compound

Disclosed is a compound useful as an anti-obesity agent. Studies have been made on compounds which have a DGAT1 inhibitory activity and are therefore promising active ingredients for pharmaceutical compositions for treating obesity, type-II diabetes, fatty liver and diseases associated with the afor...

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Main Authors KAWANO TOMOAKI, HANAZAWA TAKESHI, MORITANI HIROSHI, FUKUDOME HIROKI, NIGAWARA TAKAHIRO, YONETOKU YASUHIRO
Format Patent
LanguageChinese
English
Published 04.04.2012
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed is a compound useful as an anti-obesity agent. Studies have been made on compounds which have a DGAT1 inhibitory activity and are therefore promising active ingredients for pharmaceutical compositions for treating obesity, type-II diabetes, fatty liver and diseases associated with the aforementioned diseases, and it is confirmed that a specific diacylethylenediamine compound has an excellent DGAT1 inhibitory activity. The diacylethylenediamine compound has a DGAT1 inhibitory activity and can be used as a prophylactic and/or therapeutic agent for obesity, type-II diabetes, fatty liver and diseases associated with the aforementioned diseases.
Bibliography:Application Number: CN201080017426