4''-aralkyl carbamic acid ester clarithomycin derivative and preparation method and application thereof

The invention relates to a 4''-aralkyl carbamic acid ester clarithomycin derivative with the general formula (I) or (II), and a preparation method and application thereof. R1 represents hydrogen, acetyl or benzoyl, and R2 represents fatty alkyl, substituted aryl radical or substituted arom...

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Main Authors ZHANG LING, MA CHENCHEN, JU YONGJING, MA SHUTAO, SHEN XUECUI, SONG LINCHEN
Format Patent
LanguageChinese
English
Published 08.12.2010
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Abstract The invention relates to a 4''-aralkyl carbamic acid ester clarithomycin derivative with the general formula (I) or (II), and a preparation method and application thereof. R1 represents hydrogen, acetyl or benzoyl, and R2 represents fatty alkyl, substituted aryl radical or substituted aromatic heterocyclic alkyl. The invention also relates to a prepared intermediate product and a preparation method thereof and application of the 4''-aralkyl carbamic acid ester clarithomycin derivative to mainly resisting bacterial infection.
AbstractList The invention relates to a 4''-aralkyl carbamic acid ester clarithomycin derivative with the general formula (I) or (II), and a preparation method and application thereof. R1 represents hydrogen, acetyl or benzoyl, and R2 represents fatty alkyl, substituted aryl radical or substituted aromatic heterocyclic alkyl. The invention also relates to a prepared intermediate product and a preparation method thereof and application of the 4''-aralkyl carbamic acid ester clarithomycin derivative to mainly resisting bacterial infection.
Author SONG LINCHEN
MA SHUTAO
ZHANG LING
JU YONGJING
SHEN XUECUI
MA CHENCHEN
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Snippet The invention relates to a 4''-aralkyl carbamic acid ester clarithomycin derivative with the general formula (I) or (II), and a preparation method and...
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SubjectTerms CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
Title 4''-aralkyl carbamic acid ester clarithomycin derivative and preparation method and application thereof
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