Use of kCNQ-openers for treating or reducing the symptoms of schizophrenia

The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relate...

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Main Authors WATSON WILLIAM PATRICK, ROTTLAENDER MARIO, KHANZHIN NIKOLAY, WENZEL TORNOEE CHRISTIAN, GREVE DANIEL RODRIGUEZ, RITZEN ANDREAS
Format Patent
LanguageChinese
English
Published 04.03.2009
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Abstract The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relates to the use of selective KCNQ potassium channel openers for the preparation of a pharmaceutical composition for treating or reducing the symtoms of schizophrenia and related symptoms, disorders and diseases. Furthermore the invention relates to a method of screening for a compound, which is a selective KCNQ potassium channel opener and which is capable of having an anti-psychotic potential.
AbstractList The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relates to the use of selective KCNQ potassium channel openers for the preparation of a pharmaceutical composition for treating or reducing the symtoms of schizophrenia and related symptoms, disorders and diseases. Furthermore the invention relates to a method of screening for a compound, which is a selective KCNQ potassium channel opener and which is capable of having an anti-psychotic potential.
Author KHANZHIN NIKOLAY
ROTTLAENDER MARIO
WENZEL TORNOEE CHRISTIAN
RITZEN ANDREAS
GREVE DANIEL RODRIGUEZ
WATSON WILLIAM PATRICK
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– fullname: GREVE DANIEL RODRIGUEZ
– fullname: RITZEN ANDREAS
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Snippet The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof...
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SubjectTerms HUMAN NECESSITIES
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MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Use of kCNQ-openers for treating or reducing the symptoms of schizophrenia
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