Liposome compositions

A method of liposome-based therapy for a mammalian subject is disclosed. The method uses liposomes and/or liposomes with outer surfaces that contain an affinity moiety effective to bind specifically to a biological surface at which the therapy is aimed, and a hydrophilic polymer coating. The hydroph...

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Main Authors JIANG WENLEI, ZHANG JIA AI, KUMAR SARAN, OGORKA JOERG
Format Patent
LanguageChinese
English
Published 27.08.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract A method of liposome-based therapy for a mammalian subject is disclosed. The method uses liposomes and/or liposomes with outer surfaces that contain an affinity moiety effective to bind specifically to a biological surface at which the therapy is aimed, and a hydrophilic polymer coating. The hydrophilic polymer coating is made up of polymer chains covalently linked to surface lipid components . After a desired liposome biodistribution is achieved, the affinity agent binds to the target surface and helps internalize the liposomes.
AbstractList A method of liposome-based therapy for a mammalian subject is disclosed. The method uses liposomes and/or liposomes with outer surfaces that contain an affinity moiety effective to bind specifically to a biological surface at which the therapy is aimed, and a hydrophilic polymer coating. The hydrophilic polymer coating is made up of polymer chains covalently linked to surface lipid components . After a desired liposome biodistribution is achieved, the affinity agent binds to the target surface and helps internalize the liposomes.
Author ZHANG JIA AI
OGORKA JOERG
JIANG WENLEI
KUMAR SARAN
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HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Liposome compositions
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