Quinazolines useful as modulators of ion channels

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

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Main Authors NEUBERT TIMOTHY D, GONZALEZ JESUS E. III, SHETH URVI, BOGER JOSHUA S, FANNING LEV T. D, JOSHI PRAMOD, KRENITSKY PAUL, TERMIN ANDREAS P, HURLEY DENNIS J, WILSON DEAN M
Format Patent
LanguageChinese
English
Published 19.12.2012
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Abstract The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
AbstractList The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
Author NEUBERT TIMOTHY D
HURLEY DENNIS J
KRENITSKY PAUL
FANNING LEV T. D
TERMIN ANDREAS P
WILSON DEAN M
GONZALEZ JESUS E. III
JOSHI PRAMOD
BOGER JOSHUA S
SHETH URVI
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– fullname: BOGER JOSHUA S
– fullname: FANNING LEV T. D
– fullname: JOSHI PRAMOD
– fullname: KRENITSKY PAUL
– fullname: TERMIN ANDREAS P
– fullname: HURLEY DENNIS J
– fullname: WILSON DEAN M
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Snippet The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Quinazolines useful as modulators of ion channels
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