Substituted hydantoins for the treatment of cancer

• Main Authors: HUBY NICHOLAS J, GOODNOW ROBERT A. JR, ZHANG ZHUMING, KONG NORMAN, MCDERMOTT LEE A, MOLITERNI JOHN A
• Format: Patent
• Language: Chinese; English
• Published: 05.05.2010
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to compounds of the formula (I) which are useful in treating diseases characterized by the hyperactivity of MEK. Accordingly the compounds are useful in the treatment ofdiseases, such as, cancer, cognative and CNS disorders and inflammatory/autoimmune diseases.