Compuestos derivados de n-(1h-indazol-4-il)imidazo[1,2-a]piridin-3-carboxamida, inhbidores de la tirosina quinasa receptora de tipo iii; proceso de preparacion; composicion farmaceutica; y uso en el tratamiento de enfermedades inflamatorias, cardiovasculares, fibrosis, trastornos autoinmunes, dolor, quemaduras

• Main Authors: FREDRIK P. MARMSATER, ERIK JAMES HICKEN, DAVID A. MARESKA, MARTHA E. RODRIGUEZ, APRIL L. KENNEDY, BRYSON RAST, BRAD NEWHOUSE, QIAN ZHAO, ROBERT KIRK DELISLE, JAMES P. RIZZI, MARK C. MUNSON, MARK LAURENCE BOYS, GEORGE T. TOPALOV
• Format: Patent
• Language: Spanish
• Published: 06.12.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain...