VACCINE COMPOSITIONS AND THEIR USE
The invention relates to immunogenic compositions and their use as a vaccine for the prevention of coronavirus disease in a human subject. More specifically, the invention relates to methods of use of an immunogenic composition in the prevention of coronavirus disease in a human subject in need ther...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English French |
| Published |
29.06.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention relates to immunogenic compositions and their use as a vaccine for the prevention of coronavirus disease in a human subject. More specifically, the invention relates to methods of use of an immunogenic composition in the prevention of coronavirus disease in a human subject in need thereof, said immunogenic composition comprising: a fusion protein comprising (i) a SARS-Cov2 nucleocapsid N antigen and, (ii) a carrier protein comprising a self-assembling polypeptide derived from C4bp oligomerization domain and a positively charged tail.
L'invention concerne des compositions immunogènes et l'utilisation de celles-ci en tant que vaccin pour la prévention de la maladie à coronavirus chez un sujet humain. Plus spécifiquement, l'invention concerne des méthodes d'utilisation d'une composition immunogène dans la prévention de la maladie à coronavirus chez un sujet humain en ayant besoin, ladite composition immunogène comprenant : une protéine de fusion comprenant (i) un antigène N de nucléocapside du SARS-Cov2 et (ii) une protéine porteuse comprenant un polypeptide à auto-assemblage, dérivé du domaine d'oligomérisation C4bp, et une queue chargée positivement. |
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| AbstractList | The invention relates to immunogenic compositions and their use as a vaccine for the prevention of coronavirus disease in a human subject. More specifically, the invention relates to methods of use of an immunogenic composition in the prevention of coronavirus disease in a human subject in need thereof, said immunogenic composition comprising: a fusion protein comprising (i) a SARS-Cov2 nucleocapsid N antigen and, (ii) a carrier protein comprising a self-assembling polypeptide derived from C4bp oligomerization domain and a positively charged tail.
L'invention concerne des compositions immunogènes et l'utilisation de celles-ci en tant que vaccin pour la prévention de la maladie à coronavirus chez un sujet humain. Plus spécifiquement, l'invention concerne des méthodes d'utilisation d'une composition immunogène dans la prévention de la maladie à coronavirus chez un sujet humain en ayant besoin, ladite composition immunogène comprenant : une protéine de fusion comprenant (i) un antigène N de nucléocapside du SARS-Cov2 et (ii) une protéine porteuse comprenant un polypeptide à auto-assemblage, dérivé du domaine d'oligomérisation C4bp, et une queue chargée positivement. |
| Author | NICOLAS, FLORENCE LE VERT, ALEXANDRE HALLER, MARJORIE GUYON-GELLIN, DELPHINE |
| Author_xml | – fullname: GUYON-GELLIN, DELPHINE – fullname: HALLER, MARJORIE – fullname: LE VERT, ALEXANDRE – fullname: NICOLAS, FLORENCE |
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| DocumentTitleAlternate | COMPOSITIONS DE VACCIN ET LEUR UTILISATION |
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| Snippet | The invention relates to immunogenic compositions and their use as a vaccine for the prevention of coronavirus disease in a human subject. More specifically,... |
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| SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | VACCINE COMPOSITIONS AND THEIR USE |
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