PHTHALOCYANINE DYE COMPOUNDS, CONJUGATES AND METHODS OF USE THEREOF
Disclosed herein are phthalocyanine dyes, and conjugates thereof, useful as fluorescent reporters for bioassays, for optical imaging and as therapeutic conjugates as the photosensitizing agents in light-based therapies including photoimmuno therapy (PIT). Certain phthalocyanine dyes disclosed herein...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English French |
| Published |
14.10.2021
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Disclosed herein are phthalocyanine dyes, and conjugates thereof, useful as fluorescent reporters for bioassays, for optical imaging and as therapeutic conjugates as the photosensitizing agents in light-based therapies including photoimmuno therapy (PIT). Certain phthalocyanine dyes disclosed herein are water soluble, and possess photophysical and photochemical profiles useful for use in imaging or therapy.
La présente invention concerne des colorants à base de phtalocyanine et des conjugués de ceux-ci, utiles en tant que rapporteurs fluorescents pour des bioanalyses, pour l'imagerie optique et en tant que conjugués thérapeutiques en tant qu'agents photosensibilisants dans des photothérapies comprenant la photo-immunothérapie (PIT). Certains colorants à base de phtalocyanine selon la présente invention sont solubles dans l'eau, et possèdent des profils photophysiques et photochimiques utiles pour utilisation en imagerie ou en thérapie. |
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| AbstractList | Disclosed herein are phthalocyanine dyes, and conjugates thereof, useful as fluorescent reporters for bioassays, for optical imaging and as therapeutic conjugates as the photosensitizing agents in light-based therapies including photoimmuno therapy (PIT). Certain phthalocyanine dyes disclosed herein are water soluble, and possess photophysical and photochemical profiles useful for use in imaging or therapy.
La présente invention concerne des colorants à base de phtalocyanine et des conjugués de ceux-ci, utiles en tant que rapporteurs fluorescents pour des bioanalyses, pour l'imagerie optique et en tant que conjugués thérapeutiques en tant qu'agents photosensibilisants dans des photothérapies comprenant la photo-immunothérapie (PIT). Certains colorants à base de phtalocyanine selon la présente invention sont solubles dans l'eau, et possèdent des profils photophysiques et photochimiques utiles pour utilisation en imagerie ou en thérapie. |
| Author | BETANCORT, JUAN MAKINGS, LEW HOEY, ROBERT J WIEMANN, TORSTEN |
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| DocumentTitleAlternate | COMPOSES DE COLORANT A BASE DE PHTALOCYANINE, CONJUGUES ET LEURS PROCEDES D'UTILISATION |
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| Snippet | Disclosed herein are phthalocyanine dyes, and conjugates thereof, useful as fluorescent reporters for bioassays, for optical imaging and as therapeutic... |
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| Title | PHTHALOCYANINE DYE COMPOUNDS, CONJUGATES AND METHODS OF USE THEREOF |
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