DIRECTED CONJUGATION TECHNOLOGIES

• Main Authors: CUKAN, MICHAEL C, RASTELLI, LUCA, VIDAL, CHRISTIAN MARCEL, BERBASOVA, TETYANA, WELSCH, MATTHEW ERNEST, SPIEGEL, DAVID ADAM, IBEN, LAWRENCE GERALD, ALVAREZ, ENRIQUE, VAILL, ADA MARGARET, BUNIN, ANNA
• Format: Patent
• Language: English; French
• Published: 27.05.2021
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, p...