CDP PROTEIN SECRETION INHIBITORS

rovided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and methods of using these inhibitors. The compounds disclosed herein can be used, e.g., for the treatment of cancer, arthritis, and/or inflammation....

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Main Authors TAUNTON, JOHN WILLIAM, SHARP, PHILLIP PATRICK, MCMINN, DUSTIN
Format Patent
LanguageEnglish
French
Published 03.10.2019
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Abstract rovided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and methods of using these inhibitors. The compounds disclosed herein can be used, e.g., for the treatment of cancer, arthritis, and/or inflammation. L'invention concerne des composés qui inhibent la sécrétion de protéines, par exemple, par l'inhibition de Sec61. L'invention concerne également des compositions des composés inhibiteurs, et des procédés d'utilisation de ces inhibiteurs. Les composés de l'invention peuvent être utilisés, par exemple, pour le traitement du cancer, de l'arthrite et/ou de l'inflammation.
AbstractList rovided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and methods of using these inhibitors. The compounds disclosed herein can be used, e.g., for the treatment of cancer, arthritis, and/or inflammation. L'invention concerne des composés qui inhibent la sécrétion de protéines, par exemple, par l'inhibition de Sec61. L'invention concerne également des compositions des composés inhibiteurs, et des procédés d'utilisation de ces inhibiteurs. Les composés de l'invention peuvent être utilisés, par exemple, pour le traitement du cancer, de l'arthrite et/ou de l'inflammation.
Author TAUNTON, JOHN WILLIAM
SHARP, PHILLIP PATRICK
MCMINN, DUSTIN
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DocumentTitleAlternate INHIBITEURS DE SECRETION DE PROTEINE CDP
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Snippet rovided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title CDP PROTEIN SECRETION INHIBITORS
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