UNIVERSAL ABT COMPOUNDS AND USES THEREOF

Among other things, the present disclosure provides compounds comprising universal antibody binding moieties and targeting moieties. In some embodiments, provided compounds recruit various types of antibodies to diseased cells such as cancer cells, and induce immune activities to kill such cells. Pr...

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Bibliographic Details
Main Authors WELSCH, MATTHEW ERNEST, SPIEGEL, DAVID ADAM
Format Patent
LanguageEnglish
French
Published 31.01.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Among other things, the present disclosure provides compounds comprising universal antibody binding moieties and targeting moieties. In some embodiments, provided compounds recruit various types of antibodies to diseased cells such as cancer cells, and induce immune activities to kill such cells. Provided technologies are useful for treating various diseases including cancer. Entre autres, la présente invention concerne des composés comprenant des fractions de liaison d'anticorps universelles et des fractions de ciblage. Dans certains modes de réalisation, les composés fournis recrutent divers types d'anticorps contre des cellules malades telles que des cellules cancéreuses, et induisent des activités immunitaires pour tuer de telles cellules. Les technologies fournies sont utiles pour traiter diverses maladies y compris le cancer.
Bibliography:Application Number: CA20183069986