BICYCLIC COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS

The present disclosure is directed to inhibitors of SHP2 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same. La présente invention concerne des inhibiteurs de SHP2 et leur utilisation dans le traitement de maladies. La présente invention con...

Full description

Saved in:
Bibliographic Details
Main Authors LI, JIE JACK, BUCKL, ANDREAS, PITZEN, JENNIFER, SEMKO, CHRISTOPHER, WON, WALTER S, TZITZILONIS, CHRISTOS, WANG, GANG, AAY, NAING, KISS, GERT, MELLEM, KEVIN, KOLTUN, ELENA S, GILL, ADRIAN, BLANK, BRIAN R, JOGALEKAR, ASH
Format Patent
LanguageEnglish
French
Published 26.07.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present disclosure is directed to inhibitors of SHP2 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same. La présente invention concerne des inhibiteurs de SHP2 et leur utilisation dans le traitement de maladies. La présente invention concerne en outre des compositions pharmaceutiques comprenant lesdits inhibiteurs de SHP2.
Bibliography:Application Number: CA20183051206