HETEROCYCLIC COMPOUND

The present invention relates to N-((3S,4R)-1-((8-chloroquinoxalin-6-yl)carbonyl)-3-(4-fluorophenyl)piperidin-4-yl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide, which is a compound that can be useful for the treatment or prevention of SPT-related diseases including congenital diseases ass...

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Bibliographic Details
Main Authors IMAMURA, SHINICHI, KOJIMA, TAKUTO, NAGAI, KATSUNORI, HIRAKATA, MASAO
Format Patent
LanguageEnglish
French
Published 26.04.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to N-((3S,4R)-1-((8-chloroquinoxalin-6-yl)carbonyl)-3-(4-fluorophenyl)piperidin-4-yl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide, which is a compound that can be useful for the treatment or prevention of SPT-related diseases including congenital diseases associated with the storage of sphingolipids, such as cancer and Niemann-Pick disease, or a salt thereof. La présente invention concerne le N-((3S,4R)-1-((8-chloroquinoxalin-6-yl)carbonyl)-3-(4-fluorophényl)pipéridin-4-yl)-1-méthyl-5-(trifluorométhyl)-1H-pyrazole-3-carboxamide, qui est un composé qui peut être utile pour le traitement ou la prévention de maladies liées à la SPT, y compris des maladies congénitales associées au stockage de sphingolipides, telles que le cancer et la maladie de Niemann-Pick, ou un sel de celle-ci.
Bibliography:Application Number: CA20173041266