INHALABLE POWDER COMPOSITION COMPRISING IL-13 ANTIBODY
An inhalable powder composition comprises a) an antagonistic antibody which binds human IL-13, b) leucine and c) trehalose. The antibody may comprise a heavy chain, wherein the variable domain of the heavy chain comprises the sequence given in SEQ ID NO:3 and a light chain, wherein the variable doma...
Saved in:
Main Authors | , , , |
---|---|
Format | Patent |
Language | English French |
Published |
03.05.2018
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | An inhalable powder composition comprises a) an antagonistic antibody which binds human IL-13, b) leucine and c) trehalose. The antibody may comprise a heavy chain, wherein the variable domain of the heavy chain comprises the sequence given in SEQ ID NO:3 and a light chain, wherein the variable domain of the light chain comprises the sequence given in SEQ ID NO:1. Also described is the use of such compositions in the treatment of asthma, as well as inhalers containing such compositions.
La présente invention concerne une composition de poudre inhalable comprenant : a) un anticorps antagoniste qui se lie à l'IL -13 humaine, b) de la leucine, et c) du tréhalose. L'anticorps peut comprendre une chaîne lourde, le domaine variable de la chaîne lourde comprenant la séquence donnée dans SEQ ID NO : 3 et une chaîne légère, le domaine variable de la chaîne légère comprenant la séquence donnée dans SEQ ID NO : 1. L'invention concerne également l'utilisation de telles compositions dans le traitement de l'asthme, ainsi que des inhalateurs contenant de telles compositions. |
---|---|
AbstractList | An inhalable powder composition comprises a) an antagonistic antibody which binds human IL-13, b) leucine and c) trehalose. The antibody may comprise a heavy chain, wherein the variable domain of the heavy chain comprises the sequence given in SEQ ID NO:3 and a light chain, wherein the variable domain of the light chain comprises the sequence given in SEQ ID NO:1. Also described is the use of such compositions in the treatment of asthma, as well as inhalers containing such compositions.
La présente invention concerne une composition de poudre inhalable comprenant : a) un anticorps antagoniste qui se lie à l'IL -13 humaine, b) de la leucine, et c) du tréhalose. L'anticorps peut comprendre une chaîne lourde, le domaine variable de la chaîne lourde comprenant la séquence donnée dans SEQ ID NO : 3 et une chaîne légère, le domaine variable de la chaîne légère comprenant la séquence donnée dans SEQ ID NO : 1. L'invention concerne également l'utilisation de telles compositions dans le traitement de l'asthme, ainsi que des inhalateurs contenant de telles compositions. |
Author | KIRKE, DAVID PALFRAMAN, ROGER MAIN, MARK JONATHAN MORGAN, FRAZER GILES |
Author_xml | – fullname: MAIN, MARK JONATHAN – fullname: MORGAN, FRAZER GILES – fullname: PALFRAMAN, ROGER – fullname: KIRKE, DAVID |
BookMark | eNrjYmDJy89L5WQw8_TzcPRxdPJxVQjwD3dxDVJw9vcN8A_2DPH09wOzgzyDPf3cFTx9dA2NFRz9Qjyd_F0ieRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJvLOjsYGJgYWRhaOhMRFKAMA1KRM |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | COMPOSITION DE POUDRE INHALABLE COMPRENANT UN ANTICORPS IL -13 |
ExternalDocumentID | CA3040828A1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_CA3040828A13 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 12:54:11 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_CA3040828A13 |
Notes | Application Number: CA20173040828 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180503&DB=EPODOC&CC=CA&NR=3040828A1 |
ParticipantIDs | epo_espacenet_CA3040828A1 |
PublicationCentury | 2000 |
PublicationDate | 20180503 |
PublicationDateYYYYMMDD | 2018-05-03 |
PublicationDate_xml | – month: 05 year: 2018 text: 20180503 day: 03 |
PublicationDecade | 2010 |
PublicationYear | 2018 |
RelatedCompanies | UCB BIOPHARMA SPRL VECTURA LIMITED |
RelatedCompanies_xml | – name: VECTURA LIMITED – name: UCB BIOPHARMA SPRL |
Score | 3.1374464 |
Snippet | An inhalable powder composition comprises a) an antagonistic antibody which binds human IL-13, b) leucine and c) trehalose. The antibody may comprise a heavy... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
Title | INHALABLE POWDER COMPOSITION COMPRISING IL-13 ANTIBODY |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180503&DB=EPODOC&locale=&CC=CA&NR=3040828A1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT4NAEJ401ag3rRpbH-FguBFFFgoHYmABwfAKRa2nhseS9EIbi_Hvu7uh1YveJrvJZmaS2XnszLcAt0qlGw9NVUhTRIiEinIqGdTvSnpRqoiUBtERG06OYs1_Qc9zdT6A5XYWhuOEfnFwRGpRFbX3jt_X658ilsN7Kzd35ZIurR693HTEPjuWdQZvIjq26aaJk2ARYxNbYpyZNGtnYG0WTZT2WBTNYPbdV5sNpax_exTvGPZTeljbncCAtCM4xNuP10ZwEPXv3ZTsTW9zCloQ-1Zo2aErpMmb42YCTqI0mQWsxsTpLJgF8ZMQhJKsCFacB3bivJ-B4Lk59iXKwGIn7AJbO1aVcxi2q5ZcgCBrTSNrRq3USoFUotMgwqgqpNXNvWZQqccw_vOYyT97l3DEtMY7-JQrGHYfn-SaetmuvOH6-QZE5Hu1 |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT4NAEJ401VhvWjXWJwfDjSiypXAgBhYqq7xCUeupAbokvdDGYvz77m5o9aK3yW6ymZlkdh478y3AjVYa5n1V5soIUaqgvBgpJvO7ipEXQ0QLkxqIDyeHke6_oKfpcNqBxWYWRuCEfglwRGZRJbP3RtzXq58ilit6K9e3xYItLR_GmeXKbXasGhzeRHYdy0tiN8Yyxha25Si1WNbOwdpslijtjDg4L4-cXh0-lLL67VHGB7CbsMPq5hA6tO5DD28-XuvDXti-dzOyNb31Eegk8u3AdgJPSuI310slHIdJPCG8xiTolExI9CiRQFE1yY4y4sTu-zFIYy_DvsIYmG2FnWF7y6p2At16WdNTkFS9qlTdnGtzLUdDarAgwixLpM-rO91kUg9g8OcxZ__sXUPPz8JgFpDo-Rz2uQZFN592Ad3m45NeMo_bFFdCV982C36i |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=INHALABLE+POWDER+COMPOSITION+COMPRISING+IL-13+ANTIBODY&rft.inventor=MAIN%2C+MARK+JONATHAN&rft.inventor=MORGAN%2C+FRAZER+GILES&rft.inventor=PALFRAMAN%2C+ROGER&rft.inventor=KIRKE%2C+DAVID&rft.date=2018-05-03&rft.externalDBID=A1&rft.externalDocID=CA3040828A1 |