PYRIMIDO- OR PYRIDOPYRIDONE COMPOUND AND USE AS A CYCLIN-DEPENDENT KINASE INHIBITOR

• Main Authors: CAI, XIONG, QIAN, CHANGGENG, WANG, YANYAN, YOU, HUAJIN, LI, JUNQI, QING, YUANHUI, XUE, WEICAI
• Format: Patent
• Language: English; French
• Published: 22.09.2020
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention discloses a pyrimido- or pyridopyridone compound as shown in formula (I) and an application thereof relating to the technical field of medicament preparation. The compound can selectively suppress cyclin-dependent kinases (Cdks) CDK4 and CDK6 with almost no suppression of the a...