A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME

• Main Authors: STRAIN, MARTIN D, CARMEN, SARA, OVERED-SAYER, CATHERINE L, SCOTT, IAN C, MUSTELIN, TOMAS M, KEMP, BENJAMIN P, REES, DAVID G, LOWE, DAVID C, VOUSDEN, KATHERINE A, HOUSLAY, KIRSTY, COHEN, EMMA S, ENGLAND, ELIZABETH H, SLEEMAN, MATTHEW, BUTLER, ROBIN
• Format: Patent
• Language: English; French
• Published: 24.10.2023
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; CHEMISTRY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NEW BREEDS OF ANIMALS; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; TRAPPING

The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders. . . La présente...